The 2025 season can’t start soon enough for the Buffalo Bills.
With 2024 NFL MVP Josh Allen at the helm at quarterback, anything can happen. The team added several key pieces via the draft and free agency to help shore up some roster deficiencies.
The excitement for the season builds as Buffalo has a favorable schedule, at least on paper. Bills Wire examined this schedule and made early game-by-game predictions in the midst of OTAs.
Since AI is all the rage these days, we’ve now sought some additional guidance on how this season will turn out for Buffalo. We asked Grok to make some predictions about how this season will go for Buffalo.
Here is what Grok came up with for a game-by-game prediction for Buffalo’s final year at Highmark Stadium:
Week 1: Loss vs. Baltimore, 30-27
Buffalo opens the season with a close loss to the Baltimore Ravens. It’s a tough start for Buffalo, as they immediately lose a playoff tie-breaker at the onset of the season. The game will have a great deal of hype, as the NFL’s last two MVPs square off.
The Ravens, led by Lamar Jackson and Derrick Henry, capitalize on a strong ground game. Henry rushes for 120 yards and a touchdown, exploiting a Bills defensive front missing Larry Ogunjobi. Josh Allen throws for 250 yards and 2 TDs but is sacked three times. The game is decided by a late Ravens field goal.
Buffalo returns to the win column with a big Week 2 victory against the Jets. It’s an important game, as it gets the Bills a good start in the AFC East standings and helps with any future tie-breaking scenarios.
The Jets, under new coach Aaron Glenn and with QB Justin Fields, struggle to gel early. Allen dominates with 300 passing yards, 3 TDs, and a rushing score. Khalil Shakir emerges with 100 receiving yards. The Bills’ defense stifles Fields, forcing two turnovers.
Week 3: Win vs. Miami, 34-21
Buffalo continues its dominance over the AFC East with a convincing win over their long-time rivals.
Allen continues his dominance over Miami (12-2 record, 42 TDs). He throws for 280 yards and 3 TDs, with Dalton Kincaid catching 8 passes for 110 yards. The Dolphins’ secondary struggles, and Tyreek Hill is limited to 50 yards by Tre’Davious White.
Week 4: Win vs. New Orleans, 42-17
The dominance continues with a massive home win against the Saints. This is a game that Buffalo needed to control, as they are the far superior team in this matchup. Plus, this feels like a solid game for the defense to gain some confidence as well.
The Saints, in transition with a new coach and no clear QB (Rattler, Haener, or Shough), are overmatched. Allen throws 4 TDs, including two to Joshua Palmer. James Cook rushes for 100 yards. The Bills’ defense records 4 sacks and an interception.
Week 5: Win vs. New England, 38-24
Let’s make it four in a row. Buffalo moves to 3-0 against the AFC East. At this point, it feels like Buffalo is on cruise control already.
Despite Stefon Diggs’ return with the Patriots, the Bills roll. Allen throws for 300 yards and 2 TDs, while Cook adds 80 rushing yards and a score. Matt Milano records a pick-six off Drake Maye. The Patriots’ improved roster can’t keep up.
Week 6: Loss at Atlanta, 31-28
Ouch. What happened? It feels like there is always one game like this each season under the McDermott regime. Somehow, Buffalo struggles leading into their bye week with this loss to the Falcons.
Michael Penix Jr. and Bijan Robinson (150 all-purpose yards) challenge Buffalo’s defense. Allen throws for 270 yards and 2 TDs but is intercepted late. The Falcons’ home crowd and balanced attack secure a narrow upset.
Week 7: Bye Week
Let’s take some time to reset after that upset to Atlanta.
Week 8: Win vs. Carolina, 30-20
A 10-point victory, coming off a bye, seems a bit generous for Carolina. Sean McDermott has a perfect record following bye weeks. With two weeks to plan for the Panthers, it would seem that Buffalo could make this one a blowout. Grok doesn’t see the dominance but still predicts a victory. Even so, it’s an Elijah Moore breakout game!
Bryce Young and rookie WR Tetairoa McMillan keep it competitive, but the Bills’ defense, led by Matt Milano (10 tackles, 1 sack), shuts down the Panthers’ run game. Allen throws for 250 yards and 2 TDs, with Elijah Moore catching 6 passes for 90 yards.
Week 9: Win vs. Kansas City, 34-31
It’s a tale as old as time: Buffalo taking down Kansas City…in the regular season. The hype for this game will be massive–we can’t wait to see what it looks like in real life. For now, it’s predicted that Max Hairston will have a major impact on his young legacy in Buffalo.
A classic showdown sees Allen (350 total yards, 3 TDs) outduel Patrick Mahomes (300 passing yards, 2 TDs). The Bills’ home crowd and rest disadvantage for Kansas City (post-Monday night game) tilt the scales. Maxwell Hairston intercepts Mahomes late to seal it.
Week 10: Win at Tampa Bay, 35-27
Buffalo continues their roll with a big road win against Tampa Bay. Allen gets a bit win against the No. 1 pick in his draft class.
Baker Mayfield’s offense (Mike Evans, 100 yards) keeps pace, but Allen’s 3 touchdowns (2 passing, 1 rushing) and James Cook’s 120 all-purpose yards prove too much. The Bills’ defense forces a late fumble.
Week 11: Win at Houston, 27-24
Buffalo adds to their win column with a massive road win against the Texans. The AFC playoff picture should start to
The Bills narrowly win, capitalizing on their balanced offense. The Texans dynamic passing attack, led by CJ Stroud, challenges Buffalo’s secondary. However, Josh Allen’s dual-threat ability and the Bills stout defense secure the close win.
Week 12: Win vs. Pittsburgh, 31-21
This looks like an all-around great game for the Bills. Sean McDermott will praise the team’s complementary play between the offense and defense.
The Buffalo Bills, powered by Josh Allen’s elite playmaking and a versatile receiving duo of Keon Coleman and Khalil Shakir, will overwhelm the Pittsburgh Steelers’ inconsistent offense, despite T.J. Watt’s disruptive presence. Buffalo’s disciplined defense, led by Christian Benford and Terrel Bernard, secures a 31-21 victory in Pittsburgh.
Week 13: Loss vs. Cincinnati, 35-31
Buffalo loses a shootout against a possible playoff foe. The defense struggles in this matchup, causing some concern for the postseason run.
Joe Burrow (350 yards, 3 TDs) and Ja’Marr Chase (150 yards, 2 TDs) exploit Buffalo’s secondary in a shootout. Allen matches with 340 yards and 3 TDs, but a late defensive lapse costs the Bills.
Week 14: Win vs. New England, 34-17
Buffalo moves to 4-0 against the AFC East. A big win puts Buffalo back in the win column. There’s no doubt with this one.
The Bills dominate the rematch, with Allen throwing for 280 yards and 2 TDs. Milano and Ed Oliver combine for 3 sacks on Drake Maye. Stefon Diggs is held to 60 yards.
Week 15: Win vs. Philadelphia, 30-27
Yeah, buddy! Buffalo knocks off the defending Super Bowl Champions. It’s a big win, putting the Bills in solid contention for a long playoff run.
A tight game sees Allen (300 total yards, 2 TDs) outshine Jalen Hurts. Khalil Shakir shines with 110 receiving yards. The Bills’ defense, led by Tre’Davious White, limits DeVonta Smith to 50 yards.
Week 16: Win at Cleveland, 27-17
Buffalo may get a look at Shadeur Sanders in this game. Who knows? This is a game that Buffalo should win comfortably. At this juncture, the Browns will be looking to 2026.
The Browns’ QB competition (Watson, Flacco, or rookies) falters. Allen throws for 250 yards and 2 TDs, while Cook adds 80 rushing yards. The Bills’ defense forces two turnovers.
Week 17: Win vs. Miami, 35-24
Oh, it feels good to see the Bills take another late-season victory from the Dolphins. The Bills continue their dominance against the AFC East. The MVP talk for Allen will swell after this win.
Allen (300 yards, 3 TDs) continues his mastery over Miami. The Dolphins’ offense struggles with Tua Tagovailoa’s health concerns, and the Bills’ defense records 3 sacks.
Week 18: Win vs. New York Jets, 38-21
Buffalo closes out the season with a perfect record against the AFC East. The historic win closes out the Bills regular season time at Highmark Stadium. However, it’s far from the last game at One Bills Drive this year.
With the division clinched, the Bills play starters to secure home-field advantage. Allen throws for 280 yards and 3 TDs, while the defense, led by Matt Milano, forces two interceptions.
Postseason
Buffalo earns the No. 1 seed in the AFC with a 14-3 record. It’s massive for the Bills, as the run to the Super Bowl goes through Western New York.
Divisional Round: Win vs. Pittsburgh, 34-20
Another playoff game in Buffalo against the Steelers, and another victory for the Bills. Buffalo enjoys the extra week of rest to send Aaron Rodgers into retirement. Maybe.
The Steelers, likely a wild-card team, struggle with offensive consistency. Allen throws for 300 yards and 3 TDs, targeting Kincaid and Shakir. The Bills’ defense, with Hairston and Jackson, limits Pittsburgh’s passing game, securing a comfortable win.
AFC Championship: Win vs. Kansas City, 31-28
It’s happening. The homefield advantage gets the Bills over the hump. Let’s party like it’s 1990!
In a rematch at Highmark Stadium, the Bills finally overcome the Chiefs. Allen delivers 350 total yards and 3 TDs, including a game-winning drive. Mahomes keeps it close (300 yards, 2 TDs), but Milano’s late sack seals the victory. The home crowd and rest advantage (from the bye) prove crucial.
Super Bowl: Win vs. Philadelphia, 34-30
Grok just predicted a dream scenario for the Bills.
The season can’t start soon enough.
#Grok #gamebygame #predictions #Bills #season